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TLX1 Break Apart FISH Probe Kit
FISH sonda TLX1 Break Apart je určena k detekci přestaveb v lidském genu
TLX1
, který se nachází na chromozomovém pruhu 10q24.31. Kromě detekce zlomů, které mohou vést k translokaci částí genu, inverzi nebo jeho fúzi s jinými geny, lze sadu sond použít také k identifikaci dalších aberací
TLX1
, jako jsou delece nebo amplifikace. Přestavby a abnormální exprese genu
TLX1
, známého také jako
TCL3
nebo
HOX11
, byly pozorovány u akutní lymfoblastické leukémie (ALL), non-Hodgkinova lymfomu (NHL) a dalších malignit.
Poptat produkt
