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SNRPN/PML/CCP15 FISH Probe Kit
FISH sonda SNRPN/PML/CCP15 je určena k detekci lidského genu
SNRPN
umístěného na chromozomovém pruhu 15q11.2, lidského genu
PML
umístěného na chromozomovém pruhu 15q24 a počtu kopií chromozomu 15 v buňce. Zvýšená exprese genu
SNRPN
– známého také jako
SMN
,
PWCR
,
SM-D
,
sm-N
,
RT-LI
,
HCERN3
,
SNRNP-N
nebo
SNURF-SNRPN
– byla pozorována u některých typů solidních nádorů. Deletace otcovské kopie tohoto genu je pozorována u jedinců s Prader-Williho syndromem (PWS). Přestavby zahrnující
PML – také známý jako MYL, RNF71, PP8675
nebo
TRIM19 –
se vyskytují u různých malignit.
Poptat produkt
