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SMARCB1 Break Apart FISH Probe Kit
FISH sonda SMARCB1 Break Apart je určena k detekci přestaveb v lidském genu
SMARCB11
mapovaném na chromozomálním pruhu 22q11.23. Kromě detekce zlomů, které mohou vést k translokaci částí genu, inverzi nebo jeho fúzi s jinými geny, lze sadu sond použít také k identifikaci dalších aberací
SMARCB1
, jako jsou delece nebo amplifikace. Přeskupení a abnormální exprese genu
SMARCB11
– známého také jako
RDT, CSS3, INI1, SNF5, Snr1, BAF47, MRD15, RTPS1, Sfh1p, hSNFS, SNF5L1, SWNTS1
nebo
PPP1R144
– byly pozorovány u rabdoidních nádorů a dalších malignit a syndromů neoplastické predispozice.
Poptat produkt
