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SEC63/SMAD6 FISH Probe Kit
FISH sonda SEC63/SMAD6 je určena k detekci lidského genu
SEC63
umístěného na chromozomovém pruhu 6q21 a genu
SMAD6
na chromozomovém pruhu 15q22.31. Abnormální exprese genu
SEC63
– známého také jako
ERdj2
,
SEC63L
,
DNAJC23
nebo
PRO2507
– byla pozorována u lymfoidních malignit, jako je chronická lymfocytární leukémie (CLL) a jiné druhy rakoviny. Abnormality v genu SMAD6 – známém také jako AOVD2, MADH6, MADH7 nebo HsT17432 – jsou spojeny s vadami srdečních chlopní a vývojovými poruchami. Bylo zjištěno, že exprese SMAD6 podporuje přežití buněk u rakoviny plic a dalších typů nádorů.
Poptat produkt
