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RB1/CCP11 FISH Probe Kit
FISH sonda RB1/CCP11je určena k detekci lidského genu
RB1
umístěného na chromozomovém pruhu 13q14.2 spolu s počtem kopií chromozomu 11 na buňku. Abnormální exprese genu
RB1
– známého také jako
RB
,
pRb
,
OSRC
,
pp110
,
p105-Rb
nebo
PPP1R130
– a aneuploidie chromozomu 11 byly pozorovány u retinoblastomu, sarkomů a různých dalších dědičných a somatických typů nádorů. Současné delece
RB1
a ramene chromozomu 11q jsou časté u některých B-buněčných lymfomů.
Poptat produkt
