LSAMP/CCP3 FISH Probe Kit

The LSAMP/CCP3 FISH Probe Kit is designed to detect the human LSAMP gene located on chromosome band 3q13.31, along with the number of chromosome 3 copies per cell. Microdeletions and polymorphisms of the LSAMP genomic region have been reported during analyses of some rare congenital neuropsychiatric and behavioral disorders. Due to localized chromosomal aberrations identified in osteosarcoma cell lines, LSAMP is suspected to be a tumor suppressor gene in osteosarcoma. A novel recurrent deletion of the LSAMP locus has recently been described in African American men and found to be associated with aggressive disease progression.