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KMT2A-MLLT4 Dual Fusion/Translocation FISH Probe Kit
Fúzní/translokační FISH sonda KMT2A-MLLT4 je určena k detekci přestaveb zahrnujících lidské geny
KMT2A
a
MLLT4
, které se nacházejí na chromozomových pruzích 11q23.3 a 6q27.Přestavby mezi těmito dvěma geny, genem
KMT2A
– známým také jako
HRX
,
MLL
,
MLL1
,
TRX1
,
ALL-1
,
CXXC7
,
HTRX1
,
MLL1A
,
WDSTS
,
MLL/GAS7
nebo
TET1-MLL
– a genem
MLLT4
– také nazývaným
AF6
nebo
MLL-AF6
, byly pozorovány u akutní myeloidní leukémie (AML) a dalších malignit.
Poptat produkt
