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KAT6A Break Apart FISH Probe Kit
FISH sonda KAT6A Break Apart je určena k detekci přestaveb v lidském genu
KAT6A
, který je mapován na chromozomový pruh 8p11.21. Kromě detekce zlomů, které mohou vést k translokaci částí genu, inverzi nebo jeho fúzi s jinými geny, lze sadu sond použít také k identifikaci dalších aberací
KAT6A
, jako jsou delece nebo amplifikace. Přestavby a abnormální exprese genu
KAT6A
, známého také jako MOZ, MRD32, MYST3, MYST-3, ZNF220, RUNXBP2 nebo ZC2HC6A, byly pozorovány u akutní nelymfocytární (AML) a monocytární leukémie, myelodysplastického syndromu a dalších typů rakoviny.
Poptat produkt
