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CBFB Break Apart FISH Probe Kit
FISH sonda CBFB Break Apart je určena k detekci přestaveb v lidském genu
CBFB
umístěném na chromozomovém pruhu 16q22.1. Kromě detekce zlomů, které mohou vést k translokaci částí genu, inverzi nebo jeho fúzi s jinými geny, lze sadu sond použít také k identifikaci dalších aberací
CBFB
, jako jsou delece nebo amplifikace. Přestavby a abnormální exprese genu
CBFB
– známého také jako
CBFb
nebo
PEBP2B
– byly pozorovány u akutní myeloidní leukémie (AML) a dalších hematologických malignit.
Poptat produkt
