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BCL3 Break Apart FISH Probe Kit
FISH sonda BCL3 Break Apart je určena k detekci přestaveb v lidském genu
BCL3
, který se nachází na chromozomovém pruhu 19q13.32. Kromě detekce zlomů, které mohou vést k translokaci částí genu, inverzi nebo jeho fúzi s jinými geny, lze sadu sond použít také k identifikaci dalších aberací
BCL3
, jako jsou delece nebo amplifikace. Přestavby a abnormální exprese genu
BCL3
, známého také jako
D19S37
nebo
BCL4
, byly pozorovány u chronické lymfocytární leukémie (CLL), malého lymfocytárního lymfomu (SLL), akutní myeloidní leukémie (AML) a dalších malignit.
Poptat produkt
