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ASS1/SMAD6 FISH Probe Kit
FISH sonda ASS1/SMAD6 je určena k detekci lidského genu
ASS1
, který se nachází na chromozomovém pruhu 9q34.11, a genu
SMAD6
, který se nachází na chromozomovém pruhu 15q22.31. Abnormální exprese genu
ASS1
– nazývaného také
ASS
nebo
CTLN1
– se vyskytuje u citrulinémie typu I (CTLN1), známé také jako klasická citrulinémie. Abnormality v genu
SMAD6
– známém také jako
AOVD2
,
MADH6
,
MADH7
nebo
HsT17432
– jsou spojeny s vadami srdečních chlopní a vývojovými poruchami. Bylo zjištěno, že exprimace genu SMAD6 podporuje přežití buněk u rakoviny plic a jiných typů nádorů.
Poptat produkt
