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ALK (2p23) Break
Translokace genu ALK (anaplastická lymfomová kináza) na 2p23 byly původně spojovány s anaplastickými lymfomy, B-buněčnými lymfomy, neuroblastomy a myofibroblastickými nádory. Bylo popsáno nejméně 21 translokačních partnerů, avšak 80 % translokací zahrnuje gen NPM1 (5q35). Přestavby ALK byly popsány v případech nemalobuněčného karcinomu plic (NSCLC). Sonda ALK (2p23) Break je optimalizována pro detekci translokací zahrnujících oblast genu ALK na 2p23.
Poptat produkt
