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ABL2 Break Apart FISH Probe Kit
FISH sodna
ABL2
Break Apart je určena k detekci přestaveb v lidském lokusu
ABL2
mapovaném na chromozomový pruh 1q25.2. Kromě detekce zlomů, které mohou vést k translokaci částí genu, inverzi nebo jeho fúzi s jinými geny, lze sadu sond použít také k identifikaci dalších aberací
ABL2
, jako jsou delece nebo amplifikace. Přestavby a abnormální exprese genu
ABL2
– známého také jako
ARG
nebo
ABLL
– byly pozorovány u pacientů s akutní nelymfocytární leukémií (AML), u některých akutních lymfocytárních T-buněčných linií a u dalších malignit.
Poptat produkt
